Gene description for PDCD6IP |
Gene name |
programmed cell death 6 interacting protein |
Gene symbol |
PDCD6IP |
Other names/aliases |
AIP1 ALIX DRIP4 HP95 MCPH29 |
Species |
Homo sapiens |
Experiment description of studies that identified PDCD6IP in Glioblastoma cells |
1
|
Experiment ID | 722 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
MISEV | EVs |
Identification method | Mass spectrometry
|
PubMed ID |
25802036
|
Organism | Homo sapiens |
Experiment description | Glioblastoma-derived extracellular vesicles modify the phenotype of monocytic cells. |
Authors | de Vrij J, Maas SL, Kwappenberg KM, Schnoor R, Kleijn A, Dekker L, Luider TM, de Witte LD, Litjens M, van Strien ME, Hol EM, Kroonen J, Robe PA, Lamfers ML, Schilham MW, Broekman ML. |
Journal name |
Int J Cancer
|
Publication year | 2015 |
Sample | Glioblastoma cells |
Sample name | U87.MG/EGFRvIII |
Isolation/purification methods | Differential centrifugation Ultracentrifugation Density gradient centrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV150064: EV-METRIC:0%, 0%, 29%
|
|
|
2
|
Experiment ID | 723 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
MISEV | EVs |
Identification method | Mass spectrometry
|
PubMed ID |
25802036
|
Organism | Homo sapiens |
Experiment description | Glioblastoma-derived extracellular vesicles modify the phenotype of monocytic cells. |
Authors | de Vrij J, Maas SL, Kwappenberg KM, Schnoor R, Kleijn A, Dekker L, Luider TM, de Witte LD, Litjens M, van Strien ME, Hol EM, Kroonen J, Robe PA, Lamfers ML, Schilham MW, Broekman ML. |
Journal name |
Int J Cancer
|
Publication year | 2015 |
Sample | Glioblastoma cells |
Sample name | GS184 |
Isolation/purification methods | Differential centrifugation Ultracentrifugation Density gradient centrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV150064: EV-METRIC:0%, 0%, 29%
|
|
|
3
|
Experiment ID | 1039 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
MISEV | EVs |
Identification method | Mass spectrometry
|
PubMed ID |
27770278
|
Organism | Homo sapiens |
Experiment description | Comprehensive proteome profiling of glioblastoma-derived extracellular vesicles identifies markers for more aggressive disease. |
Authors | Mallawaaratchy DM, Hallal S, Russell B, Ly L, Ebrahimkhani S, Wei H, Christopherson RI, Buckland ME, Kaufman KL. |
Journal name |
J Neurooncol
|
Publication year | 2017 |
Sample | Glioblastoma cells |
Sample name | A172 |
Isolation/purification methods | Differential centrifugation Ultracentrifugation Filtration Density gradient centrifugation |
Flotation density | 1.09.1.11 g/mL |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
-
|
|
|
4
|
Experiment ID | 1042 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
MISEV | EVs |
Identification method | Mass spectrometry
|
PubMed ID |
27770278
|
Organism | Homo sapiens |
Experiment description | Comprehensive proteome profiling of glioblastoma-derived extracellular vesicles identifies markers for more aggressive disease. |
Authors | Mallawaaratchy DM, Hallal S, Russell B, Ly L, Ebrahimkhani S, Wei H, Christopherson RI, Buckland ME, Kaufman KL. |
Journal name |
J Neurooncol
|
Publication year | 2017 |
Sample | Glioblastoma cells |
Sample name | U251 |
Isolation/purification methods | Differential centrifugation Ultracentrifugation Filtration Density gradient centrifugation |
Flotation density | 1.09.1.11 g/mL |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
-
|
|
|
5
|
Experiment ID | 1043 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
MISEV | EVs |
Identification method | Mass spectrometry
|
PubMed ID |
27770278
|
Organism | Homo sapiens |
Experiment description | Comprehensive proteome profiling of glioblastoma-derived extracellular vesicles identifies markers for more aggressive disease. |
Authors | Mallawaaratchy DM, Hallal S, Russell B, Ly L, Ebrahimkhani S, Wei H, Christopherson RI, Buckland ME, Kaufman KL. |
Journal name |
J Neurooncol
|
Publication year | 2017 |
Sample | Glioblastoma cells |
Sample name | T98G |
Isolation/purification methods | Differential centrifugation Ultracentrifugation Filtration Density gradient centrifugation |
Flotation density | 1.09.1.11 g/mL |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
-
|
|
|
6
|
Experiment ID | 1044 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
MISEV | EVs |
Identification method | Mass spectrometry
|
PubMed ID |
27770278
|
Organism | Homo sapiens |
Experiment description | Comprehensive proteome profiling of glioblastoma-derived extracellular vesicles identifies markers for more aggressive disease. |
Authors | Mallawaaratchy DM, Hallal S, Russell B, Ly L, Ebrahimkhani S, Wei H, Christopherson RI, Buckland ME, Kaufman KL. |
Journal name |
J Neurooncol
|
Publication year | 2017 |
Sample | Glioblastoma cells |
Sample name | CCF-STTG1 |
Isolation/purification methods | Differential centrifugation Ultracentrifugation Filtration Density gradient centrifugation |
Flotation density | 1.09.1.11 g/mL |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
-
|
|
|
7
|
Experiment ID | 1071 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
MISEV | EVs |
Identification method | Mass spectrometry
|
PubMed ID |
29937354
|
Organism | Homo sapiens |
Experiment description | Apoptotic Cell-Derived Extracellular Vesicles Promote Malignancy of Glioblastoma Via Intercellular Transfer of Splicing Factors. |
Authors | Pavlyukov MS, Yu H, Bastola S, Minata M, Shender VO, Lee Y, Zhang S, Wang J, Komarova S, Wang J, Yamaguchi S, Alsheikh HA, Shi J, Chen D, Mohyeldin A, Kim SH, Shin YJ, Anufrieva K, Evtushenko EG, Antipova NV, Arapidi GP, Govorun V, Pestov NB, Shakhparonov MI, Lee LJ, Nam DH, Nakano I. |
Journal name |
Cancer Cell
|
Publication year | 2018 |
Sample | Glioblastoma cells |
Sample name | Lethally irradiated GBM157 - apoExo - biorep1 |
Isolation/purification methods | Differential centrifugation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry Western blotting |
EV-TRACK |
-
|
|
|
8
|
Experiment ID | 1072 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
MISEV | EVs |
Identification method | Mass spectrometry
|
PubMed ID |
29937354
|
Organism | Homo sapiens |
Experiment description | Apoptotic Cell-Derived Extracellular Vesicles Promote Malignancy of Glioblastoma Via Intercellular Transfer of Splicing Factors. |
Authors | Pavlyukov MS, Yu H, Bastola S, Minata M, Shender VO, Lee Y, Zhang S, Wang J, Komarova S, Wang J, Yamaguchi S, Alsheikh HA, Shi J, Chen D, Mohyeldin A, Kim SH, Shin YJ, Anufrieva K, Evtushenko EG, Antipova NV, Arapidi GP, Govorun V, Pestov NB, Shakhparonov MI, Lee LJ, Nam DH, Nakano I. |
Journal name |
Cancer Cell
|
Publication year | 2018 |
Sample | Glioblastoma cells |
Sample name | Lethally irradiated GBM157 - apoExo - biorep2 |
Isolation/purification methods | Differential centrifugation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
-
|
|
|
9
|
Experiment ID | 1274 |
Identified molecule | protein
|
Extracellular vesicle type | Microvesicles |
MISEV | EVs |
Identification method | Mass spectrometry
|
PubMed ID |
23807490
|
Organism | Homo sapiens |
Experiment description | Glioma microvesicles carry selectively packaged coding and non-coding RNAs which alter gene expression in recipient cells. |
Authors | Li CC, Eaton SA, Young PE, Lee M, Shuttleworth R, Humphreys DT, Grau GE, Combes V, Bebawy M, Gong J, Brammah S, Buckland ME, Suter CM. |
Journal name |
RNA Biol.
|
Publication year | 2013 |
Sample | Glioblastoma cells |
Sample name | U251 cells |
Isolation/purification methods | Differential centrifugation |
Flotation density | - |
Molecules identified in the study | Protein miRNA |
Methods used in the study | Mass spectrometry Microarray |
EV-TRACK |
EV130098: EV-METRIC:29%
|
|
|
10
|
Experiment ID | 1040 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
MISEV | EVs |
Identification method | Mass spectrometry Western blotting
|
PubMed ID |
27770278
|
Organism | Homo sapiens |
Experiment description | Comprehensive proteome profiling of glioblastoma-derived extracellular vesicles identifies markers for more aggressive disease. |
Authors | Mallawaaratchy DM, Hallal S, Russell B, Ly L, Ebrahimkhani S, Wei H, Christopherson RI, Buckland ME, Kaufman KL. |
Journal name |
J Neurooncol
|
Publication year | 2017 |
Sample | Glioblastoma cells |
Sample name | LN229 |
Isolation/purification methods | Differential centrifugation Ultracentrifugation Filtration Density gradient centrifugation |
Flotation density | 1.09.1.11 g/mL |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry Western blotting |
EV-TRACK |
-
|
|
|
11
|
Experiment ID | 1041 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
MISEV | EVs |
Identification method | Mass spectrometry Western blotting
|
PubMed ID |
27770278
|
Organism | Homo sapiens |
Experiment description | Comprehensive proteome profiling of glioblastoma-derived extracellular vesicles identifies markers for more aggressive disease. |
Authors | Mallawaaratchy DM, Hallal S, Russell B, Ly L, Ebrahimkhani S, Wei H, Christopherson RI, Buckland ME, Kaufman KL. |
Journal name |
J Neurooncol
|
Publication year | 2017 |
Sample | Glioblastoma cells |
Sample name | U87MG |
Isolation/purification methods | Differential centrifugation Ultracentrifugation Filtration Density gradient centrifugation |
Flotation density | 1.09.1.11 g/mL |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry Western blotting |
EV-TRACK |
-
|
|
|
12
|
Experiment ID | 1069 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
MISEV | EVs |
Identification method | Mass spectrometry Western blotting
|
PubMed ID |
29937354
|
Organism | Homo sapiens |
Experiment description | Apoptotic Cell-Derived Extracellular Vesicles Promote Malignancy of Glioblastoma Via Intercellular Transfer of Splicing Factors. |
Authors | Pavlyukov MS, Yu H, Bastola S, Minata M, Shender VO, Lee Y, Zhang S, Wang J, Komarova S, Wang J, Yamaguchi S, Alsheikh HA, Shi J, Chen D, Mohyeldin A, Kim SH, Shin YJ, Anufrieva K, Evtushenko EG, Antipova NV, Arapidi GP, Govorun V, Pestov NB, Shakhparonov MI, Lee LJ, Nam DH, Nakano I. |
Journal name |
Cancer Cell
|
Publication year | 2018 |
Sample | Glioblastoma cells |
Sample name | Untreated GBM157 - Exo - Biorep1 |
Isolation/purification methods | Differential centrifugation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry Western blotting |
EV-TRACK |
-
|
|
|
13
|
Experiment ID | 1070 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
MISEV | EVs |
Identification method | Western blotting
|
PubMed ID |
29937354
|
Organism | Homo sapiens |
Experiment description | Apoptotic Cell-Derived Extracellular Vesicles Promote Malignancy of Glioblastoma Via Intercellular Transfer of Splicing Factors. |
Authors | Pavlyukov MS, Yu H, Bastola S, Minata M, Shender VO, Lee Y, Zhang S, Wang J, Komarova S, Wang J, Yamaguchi S, Alsheikh HA, Shi J, Chen D, Mohyeldin A, Kim SH, Shin YJ, Anufrieva K, Evtushenko EG, Antipova NV, Arapidi GP, Govorun V, Pestov NB, Shakhparonov MI, Lee LJ, Nam DH, Nakano I. |
Journal name |
Cancer Cell
|
Publication year | 2018 |
Sample | Glioblastoma cells |
Sample name | Untreated GBM157 - Exo - Biorep2 |
Isolation/purification methods | Differential centrifugation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
-
|
|
|
14
|
Experiment ID | 1265 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
MISEV | EVs |
Identification method | Western blotting
|
PubMed ID |
24310399
|
Organism | Homo sapiens |
Experiment description | Extracellular vesicles modulate the glioblastoma microenvironment via a tumor suppression signaling network directed by miR-1. |
Authors | Bronisz A, Wang Y, Nowicki MO, Peruzzi P, Ansari K, Ogawa D, Balaj L, De Rienzo G, Mineo M, Nakano I, Ostrowski MC, Hochberg F, Weissleder R, Lawler SE, Chiocca EA, Godlewski J. |
Journal name |
Cancer Res.
|
Publication year | 2014 |
Sample | Glioblastoma cells |
Sample name | U87 cells - control |
Isolation/purification methods | Differential centrifugation Filtration Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV140062: EV-METRIC:33%
|
|
|
15
|
Experiment ID | 1266 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
MISEV | EVs |
Identification method | Western blotting
|
PubMed ID |
24310399
|
Organism | Homo sapiens |
Experiment description | Extracellular vesicles modulate the glioblastoma microenvironment via a tumor suppression signaling network directed by miR-1. |
Authors | Bronisz A, Wang Y, Nowicki MO, Peruzzi P, Ansari K, Ogawa D, Balaj L, De Rienzo G, Mineo M, Nakano I, Ostrowski MC, Hochberg F, Weissleder R, Lawler SE, Chiocca EA, Godlewski J. |
Journal name |
Cancer Res.
|
Publication year | 2014 |
Sample | Glioblastoma cells |
Sample name | U87 cells + miRNA-1 |
Isolation/purification methods | Differential centrifugation Filtration Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV140062: EV-METRIC:33%
|
|
|